Postdoctoral Scholar- Hoffmann Lab
Company: The J David Gladstone Institutes
Location: San Francisco
Posted on: April 1, 2026
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Job Description:
Category: Postdoc Lab/Area: Hoffmann Lab Description:
Postdoctoral Scholar – Hoffmann Lab Who we are: The Gladstone
Institutes is an independent, not-for-pro?t research institution.
Its mission is to improve the health and well-being of all people
through medical research and education in neuroscience,
cardiovascular biology, immunology, and stem cell biology. Home to
notable leaders in science and biomedicine, Gladstone comprises
five institutes as well as various centers and programs. All of its
approximately 600 members are aligned in their mission to carry out
or support science that overcomes disease. Located in an
award-winning building at the Mission Bay Campus, Gladstone offers
a competitive salary and bene?ts program. It provides an ideal
environment for those seeking to maximize and fully leverage their
potential. Consider Gladstone and make a difference in human
health. About the role: The Hoffmann Lab at the Gladstone Institute
of Virology is seeking a highly skilled and motivated individual to
join our dynamic team as a Postdoctoral Scholar. The focus of
research in the Hoffmann Lab is the development of mRNA- and
nanoparticle-based vaccine technologies against a wide range of
infectious diseases (see Hoffmann et al., Cell, 2023;
https://doi.org/10.1016/j.cell.2023.04.024 ) and cancer, as well as
gaining a deeper understanding of the immunological mechanisms that
shape vaccine-induced immune responses. Additional research
directions focus on the development of nanoparticle-based drug
delivery systems for mRNA- and small molecule-based therapeutics,
and global interactome screening platforms to map interactions
between cell surface proteins and identify new drug targets. The
successful candidate will work on research projects in these areas
depending on their interests and background, and become a member of
our vibrant and collaborative research team. What you will do:
Design, execute, and analyze experiments, both independently and in
collaboration with other team members and external research
collaborators The research projects leverage multidisciplinary
expertise in molecular biology, immunology, virology, and
bioengineering including: Design and characterization of immunogens
and self-assembling nanoparticle systems Development and evaluation
of mRNA- and protein nanoparticle-based vaccine candidates and
technologies for a wide range of infectious diseases Analysis of
vaccine-induced cellular and humoral immune responses using a
variety of methods Development and application of high-throughput
screening and in vitro evolution methodologies for various
applications Present research findings at group meetings and
external conferences Maintaining accurate records and organized
records of experimental procedures and results Collaborate with
team members on various research projects Contribute to
training/supervision of students and research associates in the
lab. What you will need: PhD in Biology, Molecular Biology,
Microbiology, Immunology, Chemistry, Bioengineering, or related
field Some background in protein engineering, immunology, virology,
and/or assay development Excellent laboratory skills Excellent
communication skills (oral and written) Ability to work in a team
environment What is preferred: Strong background in protein
engineering, immunology, virology, and/or assay development
Excellent productivity and publication record High level of
creativity and organizational skills Ability to work on several
projects in parallel as part of a team Strong interpersonal skills
and the ability to work effectively with individuals from diverse
backgrounds If interested, please send your resume / cover letter
to: Magnus Hoffmann Magnus.hoffmann@gladstone.ucsf.edu If this role
is not for you: Please stay in touch and to see a complete list of
our open career opportunities, please visit:
https://gladstone.org/careers Hiring Range: See postdoc scale:
https://gladstone.org/training/postdocs Gladstone Perks & Benefits
People –work with talented, committed, and supportive teammates
within an organization that values each member of its community. A
meaningful place to grow and learn –whether it’s your professional
skills or scientific knowledge, we have the resources and
environment to advance either so you can better support Gladstone’s
mission to drive a new era of discovery in disease-oriented science
and to mentor tomorrow’s leaders in an inspiring and excellent
environment. Healthy work/life balance –you are highly engaged and
productive at work because you can have time to recharge and enjoy
a vibrant life outside of work. Compensation –competitive salary.
Title and salary will be commensurate with education and
experience. Excellent benefits –generous medical, dental, vision,
retirement plan, paid vacation, commuter benefits, access to free
shuttle transportation. ? Gladstone is committed to providing equal
employment opportunities to all employees and applicants for
employment without regard to race, color, sex, religion, national
origin, ancestry, age, marital status, medical condition, physical
or mental disability, veteran status, sexual orientation, or any
other non-job related characteristic. We make all employment
decisions so as to further this principle of equal employment.
Keywords: The J David Gladstone Institutes, Daly City , Postdoctoral Scholar- Hoffmann Lab, Science, Research & Development , San Francisco, California